3,401 research outputs found
Borders of Belonging: Struggle and Solidarity in MixedâStatus Immigrant Families. Heide Castañeda. Stanford, CA: Stanford University Press, 2019. 334 pp.
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/162743/2/amet12941.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/162743/1/amet12941_am.pd
Health implications of an immigration raid: findings from a Latino community in the midwestern United States.
Immigration raids exemplify the reach of immigration law enforcement into the lives of Latino community members, yet little research characterizes the health effects of these raids. We examined the health implications of an immigration raid that resulted in multiple arrests and deportations and occurred midway through a community survey of a Latino population. We used linear regression following principal axis factoring to examine the influence of raid timing on immigration enforcement stress and self-rated health. We controlled for age, sex, relationship status, years in the county in which the raid occurred, children in the home, and nativity. 325 participants completed the survey before the raid and 151 after. Completing the survey after the raid was associated with higher levels of immigration enforcement stress and lower self-rated health scores. Findings indicate the negative impact of immigration raids on Latino communities. Immigration discussions should include holistic assessments of health.UL1 TR000433 - NCATS NIH HH
Can Life develop in the expanded habitable zones around Red Giant Stars?
We present some new ideas about the possibility of life developing around
sub-giant and red giant stars. Our study concerns the temporal evolution of the
habitable zone. The distance between the star and the habitable zone, as well
as its width, increases with time as a consequence of stellar evolution. The
habitable zone moves outward after the star leaves the main sequence, sweeping
a wider range of distances from the star until the star reaches the tip of the
asymptotic giant branch. If life could form and evolve over time intervals from
to years, then there could be habitable planets with
life around red giant stars. For a 1 M star at the first stages of
its post main-sequence evolution, the temporal transit of the habitable zone is
estimated to be of several 10 years at 2 AU and around 10 years at 9
AU. Under these circumstances life could develop at distances in the range 2-9
AU in the environment of sub-giant or giant stars and in the far distant future
in the environment of our own Solar System. After a star completes its first
ascent along the Red Giant Branch and the He flash takes place, there is an
additional stable period of quiescent He core burning during which there is
another opportunity for life to develop. For a 1 M star there is an
additional years with a stable habitable zone in the region from 7 to 22
AU. Space astronomy missions, such as proposed for the Terrestrial Planet
Finder (TPF) and Darwin should also consider the environments of sub-giants and
red giant stars as potentially interesting sites for understanding the
development of life
The choice between hip prosthetic bearing surfaces in total hip replacement:a protocol for a systematic review and network meta-analysis
BACKGROUND: Prosthetic hip implants have many combinations of bearing surface materials, sizes, and fixation techniques, which can determine the quality of life of patients after primary total hip replacement (THR) and the likelihood of needing revision surgery. When an implant fails, patients require revision THR, which is distressing to the patient and expensive for the health care payer. Primary THR is one of the most common elective procedures performed worldwide, with over 300,000 performed annually in the USA and over 80,000 in England and Wales. It is important to review all available randomised controlled trial (RCT) evidence to determine which implant bearing surface materials, size, and fixation technique are most effective for patients. METHODS/DESIGN: This is a protocol for a systematic review and meta-analysis of RCTs comparing outcomes of hip implant bearing surfaces, size, and fixation techniques used in THR. Implant combinations compared in the literature include four bearing surface combinations (metal-on-polyethylene, metal-on-metal, ceramic-on-polyethylene, and ceramic-on-ceramic); two femoral head sizes (large vs small heads); and four fixation techniques (uncemented, cemented, hybrid, and reverse hybrids). The primary outcome will be revision surgery. We will also collect data on patient characteristics, mortality, quality of life, and other outcomes. In network meta-analysis, we will estimate the relative effectiveness of every implant bearing surface, head size (large vs small), and fixation permutation, using evidence where implants have been compared directly in an RCT and indirectly through common comparators in different RCTs. DISCUSSION: There has been much debate about materials used for prosthetic implants in THR. Different combinations of prosthetic materials, sizes, and fixation, can vary widely in cost and fail at different rates for different patient groups. Given the number of THRs performed yearly, and the increasing use of expensive implants, it is important to review evidence to inform surgeons, patients, and health care providers of optimal implant bearing combinations for given patient characteristics. This review will inform a cost-effectiveness model that will include evidence from other sources, to determine the most effective and cost-effective implant bearing combination for patients. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD4201501943
All Six Planets Known to Orbit Kepler-11 Have Low Densities
The Kepler-11 planetary system contains six transiting planets ranging in
size from 1.8 to 4.2 times the radius of Earth. Five of these planets orbit in
a tightly-packed configuration with periods between 10 and 47 days. We perform
a dynamical analysis of the system based upon transit timing variations
observed in more than three years of \ik photometric data. Stellar parameters
are derived using a combination of spectral classification and constraints on
the star's density derived from transit profiles together with planetary
eccentricity vectors provided by our dynamical study. Combining masses of the
planets relative to the star from our dynamical study and radii of the planets
relative to the star from transit depths together with deduced stellar
properties yields measurements of the radii of all six planets, masses of the
five inner planets, and an upper bound to the mass of the outermost planet,
whose orbital period is 118 days. We find mass-radius combinations for all six
planets that imply that substantial fractions of their volumes are occupied by
constituents that are less dense than rock. The Kepler-11 system contains the
lowest mass exoplanets for which both mass and radius have been measured.Comment: 39 pages, 10 figure
Trends of child undernutrition in rural Ecuadorian communities with differential access to roads, 2004â2013
Road access can influence protective and risk factors associated with nutrition by affecting various social and biological processes. In northern coastal Ecuador, the construction of new roads created a remoteness gradient among villages, providing a unique opportunity to examine the impact of roads on child nutritional outcomes 10Â years after the road was built. Anthropometric and haemoglobin measurements were collected from 2,350 children <5Â years in Esmeraldas, Ecuador, from 2004 to 2013 across 28 villages with differing road access. Logistic generalized estimating equation models assessed the longitudinal association between village remoteness and prevalence of stunting, wasting, underweight, overweight, obesity, and anaemia. We examined the influence of socioâeconomic characteristics on the pathway between remoteness and nutrition by comparing model results with and without householdâlevel socioâeconomic covariates. Remoteness was associated with stunting (ORÂ =Â 0.43, 95% CI [0.30, 0.63]) and anaemia (ORÂ =Â 0.56, 95% CI [0.44, 0.70]). Over time, the prevalence of stunting was generally decreasing but remained higher in villages closer to the road compared to those farther away. Obesity increased (0.5% to 3%) over time; wasting was high (6%) but stable during the study period. Wealth and education partially explained the better nutritional outcomes in remote vs. road villages more than a decade after some communities gained road access. Establishing the extent to which these patterns persist requires additional years of observation.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/144663/1/mcn12588.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/144663/2/mcn12588_am.pd
Dynamic evolution in the key honey bee pathogen deformed wing virus: Novel insights into virulence and competition using reverse genetics
The impacts of invertebrate RNA virus population dynamics on virulence and infection out- comes are poorly understood. Deformed wing virus (DWV), the main viral pathogen of honey bees, negatively impacts bee health, which can lead to colony death. Despite previ- ous reports on the reduction of DWV diversity following the arrival of the parasitic mite Var- roa destructor, the key DWV vector, we found high genetic diversity of DWV in infested United States honey bee colonies. Phylogenetic analysis showed that divergent US DWV genotypes are of monophyletic origin and were likely generated as a result of diversification after a genetic bottleneck. To investigate the population dynamics of this divergent DWV, we designed a series of novel infectious cDNA clones corresponding to coexisting DWV genotypes, thereby devising a reverse-genetics system for an invertebrate RNA virus qua- sispecies. Equal replication rates were observed for all clone-derived DWV variants in single infections. Surprisingly, individual clones replicated to the same high levels as their mixtures and even the parental highly diverse natural DWV population, suggesting that complemen- tation between genotypes was not required to replicate to high levels. Mixed cloneâderived infections showed a lack of strong competitive exclusion, suggesting that the DWV geno- types were adapted to coexist. Mutational and recombination events were observed across clone progeny, providing new insights into the forces that drive and constrain virus diversifi- cation. Accordingly, our results suggest that Varroa influences DWV dynamics by causing an initial selective sweep, which is followed by virus diversification fueled by negative fre- quency-dependent selection for new genotypes. We suggest that this selection might reflect the ability of rare lineages to evade host defenses, specifically antiviral RNA interference (RNAi). In support of this hypothesis, we show that RNAi induced against one DWV strain is less effective against an alternate strain from the same population
Measuring the cosmological lepton asymmetry through the CMB anisotropy
A large lepton asymmetry in the Universe is still a viable possibility and
leads to many interesting phenomena such as gauge symmetry nonrestoration at
high temperature. We show that a large lepton asymmetry changes the predicted
cosmic microwave background (CMB) anisotropy and that any degeneracy in the
relic neutrino sea will be measured to a precision of 1% or better when the CMB
anisotropy is measured at the accuracy expected to result from the planned
satellite missions MAP and Planck. In fact, the current measurements already
put an upper limit on the lepton asymmetry of the Universe which is stronger
than the one coming from considerations of primordial nucleosynthesis and
structure formation.Comment: 4 pagex LaTex, 1 color postscript figure, uses epsf. Version
submitted to PRL. (Bug in code fixed, new figure, conclusions unchanged
Reliability of Unilateral Isometric and Dynamic Leg Press Force and Power
Strength and power are critical components of athletic performance. Athletes commonly perform sport-specific movements off a single leg, but there are few reliable, easily administered unilateral leg force and power assessments. PURPOSE: To determine 1) the reliability of unilateral leg press maximal isometric force (MIF) and peak power tests and 2) the percentage of MIF that elicits unilateral peak power during a dynamic throw. We hypothesized that the tests would be reliable for the assessment of unilateral MIF and peak power and that unilateral peak power would be achieved at 50% of MIF. METHODS: Eighteen apparently healthy, recreationally active adults (17M: 1F; 27.4 ± 5.0 years; 1.78 ± 0.01 m; 93.5 ± 22.5 kg; 3159 ± 807 N bilateral MIF) completed three testing sessions. After a brief standardized warm-up, each subject performed three maximal unilateral isometric leg presses (MIF) with each leg at 90° of knee flexion on a modified leg press sled equipped with a force plate, linear encoder, and magnetic brake. Subsequently, the sled was unlocked and loaded in ascending fashion with 30%, 40%, 50%, 60%, and 70% of MIF; with an initial knee angle of 90°, subjects used maximal effort to throw each load twice, unilaterally, with each leg. Subjects rested and reset for 10-30 s between efforts. Data were sampled at 300 Hz, low pass filtered at 4 Hz, and peak instantaneous power (W) was calculated for each throw using the measured sled force and velocity. Intraclass correlation coefficients (ICC) were computed for the highest force and power repetition at each load across the three sessions. The ICC (95% CI) and peak power output were determined for both right and left legs. ICCs were considered excellent if â„ 0.95, high if â„ 0.90, good if â„ 0.80, fair if â„ 0.70, poor if †0.70, and very poor if †0.40. RESULTS: MIF showed good reliability between sessions [ICC: 0.85 (0.62, 0.94; left leg); 0.86 (0.58, 0.95; right leg)]. Unilateral peak power also showed good to high reliability between sessions across all loads: ICC (left leg) 30%: 0.91 (0.81, 0.96); 40%: 0.91 (0.81, 0.96); 50%: 0.95 (0.88, 0.98); 60%: 0.93 (0.86, 0.97); 70%: 0.81 (0.64, 0.92); (right leg) 30%: 0.95 (0.89, 0.98); 40%: 0.94 (0.87, 0.97); 50%: 0.92 (0.84, 0.97); 60%: 0.92 (0.84, 0.97); 70%: 0.90 (0.80, 0.96). Across all three sessions, peak power by the left leg was achieved at: 30% (11 of 18 participants); 40% (6 of 18); 50% (1 of 18). Peak power by the right leg was achieved at: 30% (13 of 18 participants); 40% (4 of 18); 50% (1 of 18). CONCLUSION: Unilateral leg press MIF and peak power can be reliably assessed with a modified leg press equipped with a force plate, linear encoder, and magnetic brake in a recreationally active population. Sport teams and coaches can use single leg isometric presses and throws as reliable methods to test their athletesâ unilateral force and peak power, respectively, with loads of 30-50% MIF appropriate for peak power measurement
- âŠ